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CBP73047GFR L858R-C797S/BaF3 Kinase細胞株的詳細資料：
| CBP73047 | |
| I. Introduction | |
Cell Line Name： | EGFR L858R-C797S/BaF3 |
Gene Synonyms: | ERBB, mENA, ERBB1, HER1 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | 1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.EGFR D770_N771insG results in the insertion of a glycine (G) in the protein kinase domain of the Egfr protein between amino acids 770 and 771 (UniProt.org). D770_N771insG has not been biochemically characterized, but is predicted to result in a gain of function based on the effect of other Egfr exon 20 insertions. | |
| III. Representative Data | |
1.Sanger of EGFR L858R-C797S/BaF3
Figure 1. EGFR L858R-C797S/BaF3 C797S
Figure 2. EGFR L858R-C797S/BaF3 L858R | |
2. Anti-proliferation assay | |
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Figure 4. CTG Proliferation Assay of BaF3 EGFR L858R/C797S Cells. | |
